Bibliografia publikacji pracowników
Państwowej Szkoły Wyższej w Białej Podlaskiej
Baza tworzona przez Bibliotekę Akademii Bialskiej im. Jana Pawła II.
Zapytanie:
OLIYNYK V Liczba odnalezionych rekordów: 2
Przejście do opcji zmiany formatu | Wyświetl/ukryj etykiety | Wyświetlenie wyników w wersji do druku | Pobranie pliku do edytora | Nowe wyszukiwanie Streszczenie: Sugar substitutes are among the most widely used food additives. Increasing number of scientific research on their adverse effect on various body functions has been appearing lately. The objective of this research is to study the effect of sucralose, a sugar substitute, on the thyroid functional state. Involved in the research were 30 women, aged 19-28, estimating themselves healthy. The blood content of free and general triiodothyronine, free and general thyroxine, as well as of thyrotropic hormone was determined. Thereafter, the women were taking sucralose for a month daily in a dose of 15 mg/kg, the blood content of the hormones mentioned above having been tested again. Reliable 2.0, 1.58, and 1.46 times decrease in the blood content of free and general triiodothyronine, and general thyroxine, respectively, as well as reliable 4.41 times increase in the blood content of thyrotropic hormone (? < 0.001) has been found. Our findings on the sucralose-induced decrease in the level of thyroid hormones confirm the results of other researchers regarding sucralose as biologically inert compound that should be kept in mind when evaluating its effect on the patients with endocrine pathology.
2/2
Nr opisu: 0000040434 Autorzy: Oleksandr V. Oliynyk, O.V. Emyashev, K. Yu. Krenyov, V. Oliynyk, A. Slifirchik, B. Pereviznyk. Tytuł pracy: Porivnâl'na harakteristika vplivu neinvazivnoï j invazivnoï ventilâciï legeniv na perebig sepsisu Tytuł równoległy: Comparative characteristics of impact of moninvasive and invasive pulmonary ventilation on the sepsis course Tytuł czasopisma: Szczegóły: 2020, Vol. 87, no 1-2, p. 39--42 p-ISSN: 0023-2130 e-ISSN: 2522-1396 Charakterystyka formalna: artykuł w czasopiśmie zagranicznym Charakterystyka merytoryczna: artykuł oryginalny naukowy Charakterystyka wg MNiSW: artykuł w czasopiśmie bez IF (wykaz MEiN) Język publikacji: UKR Punktacja ministerstwa: 20.000 Słowa kluczowe ang.: noninvasive pulmonary ventilation ; sepsis https://hirurgiya.com.ua/index.php/journal/article/view/784 DOI: 10.26779/2522-1396.2020.1-2.39 Streszczenie: Objective. To compare the impact of noninvasive and invasive pulmonary ventilation on the course of sepsis, caused by severe neurotrauma, complicated by an acute respiratory distress syndrome of light degree. Materials and methods. In a randomized multicenter investigation 60 patients took part (all - the men) with diagnosis: an acute cranio-cerebral trauma, sepsis, an acute respiratory distress-syndrome of light degree. The patients' average age was (43.8 ą 8.6) yr. Method of accidental distribution of patients was used to form two groups with 30 patients in every one. In the first group a regime of coerced invasive pulmonary ventilation with the volume control (Synchronized Intermittent Mandatory Ventilation - SIMV) was applied in the treatment. In the second group a regime of noninvasive pulmonary ventilation (Constant Positive Airway Pressure - CPAP) was applied. There were established the exclusion criteria for the investigation: disorder of cognition, unstable hemodynamics, presence of roentgenological signs of pneumonia. While conduction of ventilation in the SIMV regime a respiratory volume was established and calculated by 4 - 6 ml/kg of the patient's body mass, the pressure plateau did not exceed 22.5 mm Hg, while end-expiratory positive pressure have constituted 6.0 mm Hg. While conduction of noninvasive pulmonary ventilation there was used the end-expiratory positive pressure 6.0 mm Hg value with supportive pressure up to 11.3 mm Hg, and maximal pressure did not exceeded 22.5 mm Hg. Results. Ventilation in the CPAP regime have predicted the positive end-respiratory pressure as opposite towards ventilation in the SIMV regime, and the sepsis course improvement, manifested by leukocytosis reduction in 1.3 times, procalcitonin content in the blood serum - in 2 times, occurrence of the ventilator-associated pneumonia - in 5 times and mortality index - in 3 times. Conclusion. The data obtained lead to conclusion, that application of noninvasive pulmonary ventilation in septic patients and acute respiratory distress-syndrome of light degree promotes lowering of the occurrence risk for a ventilator-associated pneumonia and mortality index.
