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Nr opisu: nyk B.^aoriginal-article^bOryginalny artykuł naukowyACZartykuł w czasopiśmie zagranicznym^a998899^b99979920.0000020.000PUNKTACJA KBNPUNKTACJA MINISTERSTWA20.000PUNKTACJA UWM^a009999.000^b009979.000^c009999.000^d009979.000202020202020Porivnâl'na harakteristika vplivu neinvazivnoï j invazivnoï ventilâciï legeniv na00000404340000001076AOartykuł oryginalny naukowyPUBLIKACJAPEŁNA PUBLIKACJAABartykuł w czasopiśmie bez IF (wykaz MNiSW)AFILIACJA PODANAUKRhttps://hirurgiya.com.ua/index.php/journal/article/view/784100^a0023-2130^bQ^iX^jXY^kQ024607^a003^b003^c2020-11-10, 13:38^d2020-11-10, 13:45^e3419948901^f3419948894^aPorivnâl'na harakteristika vplivu neinvazivnoï j invazivnoï ventilâciï legeniv na perebig sepsisu^aComparative characteristics of impact of moninvasive and invasive pulmonary ventilation on the sepsis course^aKlinichna khirurhiia^a2020^bVol. 87^cno 1-2^dp. 39--42^a0023-2130^b2522-1396^a2019/2020^a10.26779/2522-1396.2020.1-2.39^anoninvasive pulmonary ventilation^aFINAL_PUBLISHED^bCC-BY^cAT_PUBLICATION^eOPEN_JOURNAL^aObjective. To compare the impact of noninvasive and invasive pulmonary ventilation on the course of sepsis, caused by severe neurotrauma, complicated by an acute respiratory distress syndrome of light degree. Materials and methods. In a randomized multicenter investigation 60 patients took part (all - the men) with diagnosis: an acute cranio-cerebral trauma, sepsis, an acute respiratory distress-syndrome of light degree. The patients' average age was (43.8 ą 8.6) yr. Method of accidental distribution of patients was used to form two groups with 30 patients in every one. In the first group a regime of coerced invasive pulmonary ventilation with the volume control (Synchronized Intermittent Mandatory Ventilation - SIMV) was applied in the treatment. In the second group a regime of noninvasive pulmonary ventilation (Constant Positive Airway Pressure - CPAP) was applied. There were established the exclusion criteria for the investigation: disorder of cognition, unstable hemodynamics, presence of roentgenological signs of pneumonia. While conduction of ventilation in the SIMV regime a respiratory volume was established and calculated by 4 - 6 ml/kg of the patient's body mass, the pressure plateau did not exceed 22.5 mm Hg, while end-expiratory positive pressure have constituted 6.0 mm Hg. While conduction of noninvasive pulmonary ventilation there was used the end-expiratory positive pressure 6.0 mm Hg value with supportive pressure up to 11.3 mm Hg, and maximal pressure did not exceeded 22.5 mm Hg. Results. Ventilation in the CPAP regime have predicted the positive end-respiratory pressure as opposite towards ventilation in the SIMV regime, and the sepsis course improvement, manifested by leukocytosis reduction in 1.3 times, procalcitonin content in the blood serum - in 2 times, occurrence of the ventilator-associated pneumonia - in 5 times and mortality index - in 3 times. Conclusion. The data obtained lead to conclusion, that application of noninvasive pulmonary ventilation in septic patients and acute respiratory distress-syndrome of light degree promotes lowering of the occurrence risk for a ventilator-associated Autorzy: , . Tytuł czasopisma: Miejsce wydania: original-article998899009999.0000023-2130003Porivnâl'na harakteristika vplivu neinvazivnoï j invazivnoï ventilâciï legeniv na perebig sepsisuComparative characteristics of impact of moninvasive and invasive pulmonary ventilation on the sepsis courseKlinichna khirurhiia20200023-21302019/202010.26779/2522-1396.2020.1-2.39noninvasive pulmonary ventilationFINAL_PUBLISHEDObjective. To compare the impact of noninvasive and invasive pulmonary ventilation on the course of sepsis, caused by severe neurotrauma, complicated by an acute respiratory distress syndrome of light degree. Materials and methods. In a randomized multicenter investigation 60 patients took part (all - the men) with diagnosis: an acute cranio-cerebral trauma, sepsis, an acute respiratory distress-syndrome of light degree. The patients' average age was (43.8 ą 8.6) yr. Method of accidental distribution of patients was used to form two groups with 30 patients in every one. In the first group a regime of coerced invasive pulmonary ventilation with the volume control (Synchronized Intermittent Mandatory Ventilation - SIMV) was applied in the treatment. In the second group a regime of noninvasive pulmonary ventilation (Constant Positive Airway Pressure - CPAP) was applied. There were established the exclusion crite Wydawca: Oryginalny artykuł naukowyACZartykuł w czasopiśmie zagranicznym99979920.0000020.000PUNKTACJA KBNPUNKTACJA MINISTERSTWA20.000PUNKTACJA UWM009979.000Q003Vol. 872522-1396CC-BY Rok wydania: 009999.0002020-11-10, 13:38no 1-2AT_PUBLICATION Charakterystyka formalna: the sepsis course^aKlinichna khirurhiia^a2020^bVol. 87^cno 1-2^dp. 39--42^a0023-2130^b2522-1396^a2019/2020^a10.26779/2522-1396.2020.1-2.39^anoninvasive pulmonary ventilation^aFINAL_PUBLISHED^bCC-BY^cAT_PUBLICATION^eOPEN_JOURNAL^aObjective. To compare the impact of noninvasive and invasive pulmonary ventilation on the course of sepsis, caused by severe neurotrauma, complicated by an acute respiratory distress syndrome of light degree. Materials and methods. In a randomized multicenter investigation 60 patients took part (all - the men) with diagnosis: an acute cranio-cerebral trauma, sepsis, an acute respiratory distress-syndrome of light degree. The patients' average age was (43.8 ą 8.6) yr. Method of accidental distribution of patients was used to form two groups with 30 patients in every one. In the first group a regime of coerced invasive pulmonary ventilation with the volume control (Synchronized Intermittent Mandatory Ventilation - SIMV) was applied in the treatment. In the second group a regime of noninvasive pulmonary ventilation (Constant Positive Airway Pressure - CPAP) was applied. There were established the exclusion criteria for the investigation: disorder of cognition, unstable hemodynamics, presence of roentgenological signs of pneumonia. While conduction of ventilation in the SIMV regime a respiratory volume was established and calculated by 4 - 6 ml/kg of the patient's body mass, the pressure plateau did not exceed 22.5 mm Hg, while end-expiratory positive pressure have constituted 6.0 mm Hg. While conduction of noninvasive pulmonary ventilation there was used the end-expiratory positive pressure 6.0 mm Hg value with supportive pressure up to 11.3 mm Hg, and maximal pressure did not exceeded 22.5 mm Hg. Results. Ventilation in the CPAP regime have predicted the positive end-respiratory pressure as opposite towards ventilation in the SIMV regime, and the sepsis course improvement, manifested by leukocytosis reduction in 1.3 times, procalcitonin content in the blood serum - in 2 times, occurrence of the ventilator-associated pneumonia - in 5 times and mortality index - in 3 times. Conclusion. The data obtained lead to conclusion, that application of noninvasive pulmonary ventilation in septic patients and acute respiratory distress-syndrome of light degree promotes lowering of the occurrence risk for a ventilator-associated pneumonia and mortality index.^asepsis Charakterystyka wg MNiSW:
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Nr opisu: Autorzy: . Tytuł pracy: Tryb dostępu: 009999.000003 : 009994.000 : R : 003, 009999.000, 2 Charakterystyka formalna: stress syndrome under various regimens is the issue of today. The actual view on the topic being diverse, in most scientists view further research is needed. The objective of the research has been to compare the treatment outcomes of the patients with severe neurotrauma, sepsis, and mild acute respiratory distress syndrome (ARDS), depending on whether forced ventilation with regulated volume or noninvasive ventilation (NIV) is used as the regimen of ventilation support. Materials and methods: Involved in the randomized multicenter research were 60 men (mean age 43.8+8.6 years) with craniocerebral trauma, sepsis, and mild ARDS. The patients were divided into 2 groups (30 men in each) using random distribution method. In group 1, synchronized intermittent mandatory ventilation (SIMV) with regulated volume was used, whereas in group 2 continuous positive airway pressure (?PAP) was applied. Excluded from the research were those with impairment of consciousness, unstable hemodynamics, and X-ray evidence of pneumonia. In SIMV forced ventilation, respiratory volume was based on 4-6 ml/kg, the plateau level not exceeding 30 mbar, 8 mbar positive end-expiratory pressure (PEEP) being applied. Non-invasive lung ventilation was performed at 8 mbar PEEP, up to 15 mbar support pressure, the maximum pressure not exceeding 30 mbar. Results: In comparison with invasive lung ventilation, application of non-invasive lung ventilation in the patients with severe craniocerebral trauma, sepsis, and mild ARDS has been shown to contribute to the improvement of disease course, revealing itself in 1.32 times leukocytosis decrease, 2 times reduction in the blood serum procalcitonin content, as well as in 5 and 3 times decrease in the incidence of ventilator-associated pneumonias and mortality rate, respectively. Conclusion: Our findings taken into consideration, it may be concluded that application of non-invasive lung ventilation in the patients with mild ARDS and sepsis is appropriate, this treatment technique decreasing both the risk of ventilator-associated pneumonias and mortality rate. It can be argued that the application of non-invasive lung ventilation reduces the activity of septic process.^anon-invasive lung ventilation^asepsis Charakterystyka merytoryczna: Język publikacji: Praca recenzowana Słowa kluczowe ang.: [sprawdź dostępność w katalogu AB]
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Autorzy: , . Tytuł pracy: Szczegóły: ISBN: 998899009999.000003Dosvid likuvannâ hvorih na tâžku čerepno-mozkovu travmu, uskladnenu tâžkim sepsisom, y viddilenni anesteziologiï ta intensivnoïterapiï Ternopil'skoï universitets'koï likarniExperience of treatment of severe brain injury, complicated by severe sepsis in De Tryb dostępu: original-article998899009999.000 : Oryginalny artykuł naukowyACZartykuł w czasopiśmie zagranicznym : 999999 : 009999.000, 009999.000 Słowa kluczowe: ; Słowa kluczowe ang.: ; Streszczenie: Streszczenie: sepsasepsisKopia dostępna w Dziale Gromadzenia, Opracowania i Kontroli Zbiorów Biblioteki PSW.The results of treatment of 72 patients with severe traumatic brain injury, complicated by severe sepsis, treated at the Department of Anesthesiology and Intensive Care of Ternopil Medical University Hospital in 2013-2014. The death rate from this disease in the clinic was in 2013-2014 - 29,7 %. among patients treated in department with diagnose of severe brain trauma, patients with sepsis were occurred in 23,9 % cases. We used the protocol for the treatment of severe traumatic brain injury by american Association of Neurosurgeons (2007). Acute respiratory distress syndrome, as complication of sepsis was successfully treated in 73,3 % of cases. In addition to using of traditional ventilation, kinesiotherapy, oxygenotherapy was used the pulse therapy with glucocorticoids. 18 % patients carried ventilation longer than 30 days. Over the last 3 years we observed the revealed increased of sensitivity of microflora to chloramphenicol, streptomycin, gentamicin.Ślifirczyk, Annauraz mózgowo-czaszkowybrain injuryantybiotykoopornośćantibiotic resistancetlenoterapiaoxygenotherapykinezyterapiakinesiotherapyPain, Anaesthesia and Intensive Care