Bibliografia publikacji pracowników
Państwowej Szkoły Wyższej w Białej Podlaskiej
Baza tworzona przez Bibliotekę Akademii Bialskiej im. Jana Pawła II.
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MATUSZEWSKA RENATA Liczba odnalezionych rekordów: 3
Przejście do opcji zmiany formatu | Wyświetl/ukryj etykiety | Wyświetlenie wyników w wersji do druku | Pobranie pliku do edytora | Nowe wyszukiwanie Streszczenie: Legionella bacteria are commonly found in natural aquatic environments such as rivers, lakes, ponds and hot springs. Legionella infection occurs through the inhalation of water-air aerosol generated, for example, by showers or hot tubs. The most common species responsible for infection is Legionella pneumophila, which can cause Pontiac fever, and Legionnaires' disease, as well as a rare extrapulmonary form. The aim of the study's is to assess the susceptibility of Legionella pneumophila bacteria isolated from water systems of public buildings in Poland to antibiotics and chemotherapeutic agents used in the treatment of Legionellosis pneumonia. Material and methods: A total of 100 L. pneumophila strains isolated from public buildings, such as hospitals and water recreation facilities, were used for the study. The drug sensitivity of the following antibiotics was determined: erythromycin, azithromycin, ciprofloxacin, levofloxacin, rifampicin, trimethoprim-sulfamethoxazole and tetracycline. Mean MIC50 and MIC90 values were read using accepted standards. Results: The highest mean MIC value was obtained for tetracycline 6,130+/-0,353 ľg/ml (with a range from 1,500 ľg/ml to 16,000 ľg/ml. In contrast, the lowest MIC was recorded with rifampicin: 0.020+/-0.037 ľg/ml (with a range from 0.016 ľg/ml to 0.380 ľg/ml). Conclusions: The lowest biocidal concentration was found for levofloxacin, the highest for tetracycline. The highest MIC50 and MIC90 values were found for tetracycline and the lowest for rifampicin. The highest biocidal values were found for azithromycin and the lowest for tetracycline. Projekt/grant: Ocena wrażliwości bakterii Legionella pneumophilla na antybiotyki : Fundusz Rozwoju Nauki PSW, PB/28/2020
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Nr opisu: 0000033474 Autorzy: Agnieszka Sikora, Iwona Gładysz, Maria Kozioł-Montewka, Małgorzata Wójtowicz-Bobin, Tomasz Stańczak, Renata Matuszewska, Bożena Krogulska. Tytuł pracy: Assessment of antibiotic susceptibility of Legionella pneumophila isolated from water systems in Poland Tytuł czasopisma: Szczegóły: 2017, Vol. 24, no. 1, p. 70--73 p-ISSN: 1232-1966 e-ISSN: 1898-2263 Charakterystyka formalna: artykuł w czasopiśmie polskim Charakterystyka merytoryczna: artykuł oryginalny naukowy Charakterystyka wg MNiSW: artykuł w czasopiśmie z IF (wykaz MEiN) Język publikacji: ENG Wskaźnik Impact Factor ISI: 1.116 Punktacja ministerstwa: 30.000 Praca recenzowana Słowa kluczowe ang.: Legionella pneumophila ; susceptibility ; E-test ; minimum inhibitory concentration Uwaga: Kopia dostępna w Sekcji Bibliometrii. http://www.aaem.pl/Assessment-of-antibiotic-susceptibility-of-Legionella-pneumophila-isolated-from-water-systems-in-Poland,72609,0,2.html DOI: 10.5604/12321966.1234048 Streszczenie: Introduction and objective. Several studies have reported therapy failures in patients with legionnaires'disease; however, antimicrobial resistance of clinical and environmental isolates of Legionella spp. has not yet been documented. Routine susceptibility testing of Legionella spp. is not recommended because of difficulties in determining standard minimal inhibitory concentration values. The purpose of this study was to analyze the antimicrobial susceptibility of Legionella pneumophila. strains isolated from a water supply system. Materials and method. Twenty-eight isolates of L. pneumophila (16 - L. pneumophila SG 1, 12 - L. pneumophila SG 2-14) obtained from water systems in public buildings in Poland were tested. Susceptibility testing was performed using the E-test method. The tested antibiotic were azithromycin, ciprofloxacin, and rifampicin. The medium used for the susceptibility testing was BCYE-, a special medium for Legionella cultivation. Results. Among the tested strains, L. pneumophila was the only one resistant to azithromycin. It was a strain of L. pneumophila SG 2-14 isolated from the water system in a sanitorium. All isolates were found to be sensitive to ciprofloxacin and rifampicin. However, the azithromycin-resistant strain exhibited higher ciprofloxacin and rifampicin MIC (1.5 ?g/ml, and 0.19 ?g/ml, respectively). The MIC50 for azithromycin, ciprofloxacin, and rifampicin were 0,032, 0,125, and 0,003 ?g/ml, respectively. The MIC90 for azithromycin, ciprofloxacin, and rifampicin were 0,032, 0,125, and 0,003 ?g/ml, respectively. Conclusions. Azithromycin resistance was found in one strain of L. pneumophila SG 2-14, but the resistance mechanism is unknown and needs further study. It is possible that therapeutic failures in Legionnaires' disease may be associated with bacterial resistance which should be taken into account. The antibiotic sensitivity testing described in this study could be helpful in detecting the resistance of clinical L. pneumophila isolates. Ciprofloxacin and rifampicin have good in vitro activity against environmental L. pneumophila SG 1 and SG 2-14 in Poland.
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Nr opisu: 0000029134 Autorzy: Agnieszka Sikora, Bożena Krogulska, Renata Matuszewska, T.S. Stańczak, Małgorzata Wójtowicz-Bobin, Iwona Gładysz, Maria Kozioł-Montewka. Tytuł pracy: Assessment of Legionella pneumophila antibiotic susceptibility Tytuł czasopisma: Szczegóły: 2014, Vol. 21, Suppl. 1, p. 92 p-ISSN: 1201-9712 Uwagi: 16th International Congress on Infectious Diseases (ICID) Abstracts. Abstract no. 40.031. Poster Presentation. Charakterystyka formalna: streszczenie zjazdowe w suplemencie zagranicznym Charakterystyka merytoryczna: konferencja naukowa międzynarodowa Język publikacji: ENG Słowa kluczowe: Legionella pneumophila ; antybiotyk Słowa kluczowe ang.: Legionella pneumophila ; antibiotic Uwaga: Kopia dostępna w Dziale Gromadzenia, Opracowania i Kontroli Zbiorów Biblioteki PSW Inne bazy podające opis:
